Targeted Disruption of <i>NFATc3</i>, but Not <i>NFATc4</i>, Reveals an Intrinsic Defect in Calcineurin-Mediated Cardiac Hypertrophic Growth

A calcineurin-nuclear factor of activated T cells (NFAT) regulatory pathway has been implicated in the control of cardiac hypertrophy, suggesting one mechanism whereby alterations in intracellular calcium handling are linked to the expression of hypertrophy-associated genes. Although recent studies...

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Bibliographic Details
Main Authors: Benjamin J. Wilkins, León J. De Windt, Orlando F. Bueno, Julian C. Braz, Betty J. Glascock, Thomas F. Kimball, Jeffery D. Molkentin
Format: Artigo
Language:English
Published: 2002
Online Access:https://doi.org/10.1128/mcb.22.21.7603-7613.2002
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