Targeted Disruption of <i>NFATc3</i>, but Not <i>NFATc4</i>, Reveals an Intrinsic Defect in Calcineurin-Mediated Cardiac Hypertrophic Growth
A calcineurin-nuclear factor of activated T cells (NFAT) regulatory pathway has been implicated in the control of cardiac hypertrophy, suggesting one mechanism whereby alterations in intracellular calcium handling are linked to the expression of hypertrophy-associated genes. Although recent studies...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Language: | English |
Published: |
2002
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Online Access: | https://doi.org/10.1128/mcb.22.21.7603-7613.2002 |
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