Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
Maintenance of endoplasmic reticulum (ER) function is achieved in part through Ire1 (inositol-requiring enzyme 1), a transmembrane protein activated by protein misfolding in the ER. The cytoplasmic nuclease domain of Ire1 cleaves the messenger RNA (mRNA) encoding XBP-1 (X-box-binding protein 1), ena...
में बचाया:
| मुख्य लेखकों: | , , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | अंग्रेज़ी |
| प्रकाशित: |
2009
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| ऑनलाइन पहुंच: | https://doi.org/10.1083/jcb.200903014 https://rupress.org/jcb/article-pdf/186/3/323/1899665/jcb_200903014.pdf |
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