Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats
We hypothesized that perinatal inhibition of soluble epoxide hydrolase (SEH), which metabolizes epoxyeicosatrienoic acids in the arachidonic acid (AA) cascade, with an orally active SEH inhibitor, 12-(3-adamantan-1-yl-ureido)-dodecanoic acid (AUDA), would persistently reduce blood pressure (BP) in a...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Englisch |
| Veröffentlicht: |
2011
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| Online-Zugang: | https://doi.org/10.1152/ajpendo.00710.2010 |
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