Combination Therapy Targeting Both Tumor-Initiating and Differentiated Cell Populations in Prostate Carcinoma
Abstract Purpose: The cancer stem cell hypothesis predicts that standard prostate cancer monotherapy eliminates bulk tumor cells but not a tumor-initiating cell population, eventually leading to relapse. Many studies have sought to determine the underlying differences between bulk tumor and cancer s...
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Hauptverfasser: | , , , , , , , , , , , |
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Format: | Artigo |
Sprache: | Englisch |
Veröffentlicht: |
2010
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Online-Zugang: | https://doi.org/10.1158/1078-0432.ccr-10-1601 |
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