Combination Therapy Targeting Both Tumor-Initiating and Differentiated Cell Populations in Prostate Carcinoma

Abstract Purpose: The cancer stem cell hypothesis predicts that standard prostate cancer monotherapy eliminates bulk tumor cells but not a tumor-initiating cell population, eventually leading to relapse. Many studies have sought to determine the underlying differences between bulk tumor and cancer s...

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Hauptverfasser: Anna Dubrovska, Jimmy Elliott, Richard J. Salamone, Sungeun Kim, Lindsey J. Aimone, John R. Walker, J. P. Watson, Sauveur-Michel Maira, Carlos Garcı́a-Echeverrı́a, Charles Y. Cho, Venkateshwar A. Reddy, Peter G. Schultz
Format: Artigo
Sprache:Englisch
Veröffentlicht: 2010
Online-Zugang:https://doi.org/10.1158/1078-0432.ccr-10-1601
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