SC29EK, a Peptide Fusion Inhibitor with Enhanced α-Helicity, Inhibits Replication of Human Immunodeficiency Virus Type 1 Mutants Resistant to Enfuvirtide
ABSTRACT Peptides derived from the α-helical domains of human immunodeficiency virus (HIV) type 1 (HIV-1) gp41 inhibit HIV-1 fusion to the cell membrane. Enfuvirtide (T-20) is a peptide-based drug that targets the step of HIV fusion, and as such, it effectively suppresses the replication of HIV-1 st...
-д хадгалсан:
Үндсэн зохиолчид: | , , , , , , , , , , |
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Формат: | Artigo |
Хэл сонгох: | англи |
Хэвлэсэн: |
2008
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Онлайн хандалт: | https://doi.org/10.1128/aac.01211-08 |
Шошгууд: |
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