Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis
Disappearance of TAR-DNA-binding protein 43 kDa (TDP-43) from the nucleus contributes to the pathogenesis of amyotrophic lateral sclerosis (ALS), but the nuclear function of TDP-43 is not yet fully understood. TDP-43 associates with nuclear bodies including Gemini of coiled bodies (GEMs). GEMs contr...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Αγγλικά |
| Έκδοση: |
2013
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| Διαθέσιμο Online: | https://doi.org/10.1093/hmg/ddt262 https://academic.oup.com/hmg/article-pdf/22/20/4136/17260539/ddt262.pdf |
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