PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase

Obesity and metabolic syndrome are associated with an increased risk for lipotoxic cardiomyopathy, which is strongly correlated with excessive accumulation of lipids in the heart. Obesity- and type-2-diabetes-related disorders have been linked to altered expression of the transcriptional cofactor PG...

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Bibliografiset tiedot
Päätekijät: Soda Diop, Jumana Bisharat‐Kernizan, Ryan T. Birse, Sean Oldham, Karen Ocorr, Rolf Bodmer
Aineistotyyppi: Artigo
Kieli:englanti
Julkaistu: 2015
Linkit:https://doi.org/10.1016/j.celrep.2015.02.022
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