Combinatorial Approach to Determine Functional Group Effects on Lipidoid-Mediated siRNA Delivery
The application of RNA interference (RNAi), either in the clinic or in the laboratory, requires safe and effective delivery methods. Here, we develop a combinatorial approach to synthesize a library of delivery vectors based on two lipid-like substrates with known siRNA delivery capabilities. Member...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | inglés |
| Publicado: |
2010
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| Acceso en línea: | https://doi.org/10.1021/bc100041r |
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