Combinatorial Approach to Determine Functional Group Effects on Lipidoid-Mediated siRNA Delivery

The application of RNA interference (RNAi), either in the clinic or in the laboratory, requires safe and effective delivery methods. Here, we develop a combinatorial approach to synthesize a library of delivery vectors based on two lipid-like substrates with known siRNA delivery capabilities. Member...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kerry P. Mahon, Kevin T. Love, Kathryn A. Whitehead, June Qin, Akin Akinc, Elizaveta S. Leshchiner, Ignaty Leshchiner, Róbert Langer, Daniel G. Anderson
स्वरूप: Artigo
भाषा:अंग्रेज़ी
प्रकाशित: 2010
ऑनलाइन पहुंच:https://doi.org/10.1021/bc100041r
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