Defective ATP-dependent bile canalicular transport of organic anions in mutant (TR-) rats with conjugated hyperbilirubinemia.
TR- mutant Wistar rats secrete markedly fewer organic anions other than bile acids from the liver into the bile than do control rats. Fluorescence-image analysis of isolated normal and TR- hepatocyte "doublets", which retain a bile canaliculus between them, revealed that normal hepatocytes...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | anglais |
| Publié: |
1990
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| Accès en ligne: | https://doi.org/10.1073/pnas.87.9.3557 |
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