Galectin-3 regulates myofibroblast activation and hepatic fibrosis
Central to fibrogenesis and the scarring of organs is the activation of fibroblasts into matrix-secreting myofibroblasts. We demonstrate that Galectin-3 expression is up-regulated in established human fibrotic liver disease and is temporally and spatially related to the induction and resolution of e...
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Autores principales: | , , , , , , , , |
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Formato: | Artigo |
Lenguaje: | inglés |
Publicado: |
2006
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Acceso en línea: | https://doi.org/10.1073/pnas.0511167103 |
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