Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5‐A3 genetic locus and lung cancer risk
Recent genome-wide association studies of lung cancer have shown that the CHRNA5-A3 region on chromosome 15q24-25.1 is strongly associated with an increased risk of lung cancer and nicotine dependence, and is thought to be associated with chronic obstructive pulmonary disease as well. However, it ha...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://doi.org/10.1002/cncr.25085 |
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