Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform
Senescence may function as a two-edged sword that brings unexpected consequences to organisms. Here we provide evidence to support this theory by showing that the absence of the Brca1 full-length isoform causes senescence in mutant embryos and cultured cells as well as aging and tumorigenesis in adu...
Spremljeno u:
| Glavni autori: | , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | engleski |
| Izdano: |
2003
|
| Online pristup: | https://doi.org/10.1101/gad.1050003 http://genesdev.cshlp.org/content/17/2/201.full.pdf |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|