Akt Promotes Survival of Cardiomyocytes In Vitro and Protects Against Ischemia-Reperfusion Injury in Mouse Heart
Background —IGF-1 has been shown to protect myocardium against death in animal models of infarct and ischemia-reperfusion injury. In the present study, we investigated the role of the IGF-1–regulated protein kinase Akt in cardiac myocyte survival in vitro and in vivo. Methods and Results —IGF-1 prom...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | английский |
| Опубликовано: |
2000
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| Online-ссылка: | https://doi.org/10.1161/01.cir.101.6.660 https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.101.6.660 |
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