Hepatocyte Growth Factor-regulated Tyrosine Kinase Substrate (HRS) Mediates Post-endocytic Trafficking of Protease-activated Receptor 2 and Calcitonin Receptor-like Receptor
The E3 ligase c-Cbl ubiquitinates protease-activated receptor 2 (PAR2), which is required for post-endocytic sorting of PAR2 to lysosomes, where degradation arrests signaling. The mechanisms of post-endocytic sorting of ubiquitinated receptors are incompletely understood. Here, we investigated the r...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | ingelesa |
| Argitaratua: |
2007
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| Sarrera elektronikoa: | https://doi.org/10.1074/jbc.m702974200 http://www.jbc.org/article/S0021925819514715/pdf |
| Etiketak: |
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