TNF‐α‐mediated reduction in PGC‐1α may impair skeletal muscle function after cigarette smoke exposure

Abstract Skeletal muscle dysfunction contributes to exercise limitation in COPD. In this study cigarette smoke exposure was hypothesized to increase expression of the inflammatory cytokine, TNF‐α, thereby suppressing PGC‐1α, and hence affecting down stream molecules that regulate oxygen transport an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kechun Tang, Peter D. Wagner, Ellen C. Breen
Formatua: Artigo
Hizkuntza:ingelesa
Argitaratua: 2009
Sarrera elektronikoa:https://doi.org/10.1002/jcp.21955
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