Primary lysosomal dysfunction causes cargo-specific deficits of axonal transport leading to Alzheimer-like neuritic dystrophy
Abnormally swollen regions of axons and dendrites (neurites) filled mainly with autophagy-related organelles represent the highly characteristic and widespread form of "neuritic dystrophy" in Alzheimer disease (AD), which implies dysfunction of autophagy and axonal transport. In this punct...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | anglais |
| Publié: |
2011
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| Accès en ligne: | https://doi.org/10.4161/auto.7.12.17956 https://www.tandfonline.com/doi/pdf/10.4161/auto.7.12.17956?needAccess=true |
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