Modulating Microtubule Stability Enhances the Cytotoxic Response of Cancer Cells to Paclitaxel

The extracellular matrix protein TGFBI enhances the cytotoxic response of cancer cells to paclitaxel by affecting integrin signals that stabilize microtubules. Extending the implications of this knowledge, we tested the more general hypothesis that cancer cell signals which increase microtubule stab...

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Bibliographic Details
Main Authors: Ahmed A. Ahmed, Xiaoyan Wang, Zhen Lü, Juliet Goldsmith, Xiao-Feng Le, Geoffrey Grandjean, Geoffrey Bartholomeusz, Bradley M. Broom, Robert C. Bast
Format: Artigo
Language:English
Published: 2011
Online Access:https://doi.org/10.1158/0008-5472.can-11-0025
https://aacrjournals.org/cancerres/article-pdf/71/17/5806/2657501/5806.pdf
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