Modulating Microtubule Stability Enhances the Cytotoxic Response of Cancer Cells to Paclitaxel

The extracellular matrix protein TGFBI enhances the cytotoxic response of cancer cells to paclitaxel by affecting integrin signals that stabilize microtubules. Extending the implications of this knowledge, we tested the more general hypothesis that cancer cell signals which increase microtubule stab...

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Main Authors: Ahmed A. Ahmed, Xiaoyan Wang, Zhen Lü, Juliet Goldsmith, Xiao-Feng Le, Geoffrey Grandjean, Geoffrey Bartholomeusz, Bradley M. Broom, Robert C. Bast
格式: Artigo
語言:英语
出版: 2011
在線閱讀:https://doi.org/10.1158/0008-5472.can-11-0025
https://aacrjournals.org/cancerres/article-pdf/71/17/5806/2657501/5806.pdf
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