Pharmacodynamics, pharmacokinetics, and safety of multiple doses of FTY720 in stable renal transplant patients: a multicenter, randomized, placebo-controlled, phase I study

Background. FTY720, a novel immunomodulator, displays potent immunosuppressive activity in a variety of preclinical transplant models. This study examined the safety, pharmacodynamics, and pharmacokinetics of multiple doses of FTY720 in stable renal transplant patients. Methods. This randomized, mul...

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Main Authors: Barry D. Kahan, Janet L. Karlix, Ronald M. Ferguson, Alan B. Leichtman, Shamkant Mulgaonkar, Thomas A. Gonwa, Andrej Skerjanec, Robert Schmouder, Lawrence Chodoff
Format: Artigo
Jezik:angleščina
Izdano: 2003
Online dostop:https://doi.org/10.1097/01.tp.0000084822.01372.ac
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