Glycogen synthase kinase-3β phosphorylates tau protein at multiple sites in intact cells
Hyperphosphorylated tau protein is the major constituent of the paired helical filament (PHF), the major fibrous component of the neurofibrillary lesions of Alzheimer's disease (AD). Hyperphosphorylation of tau is believed to be the critical event that leads to filament assembly. Identification...
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| Main Authors: | , , , |
|---|---|
| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
1995
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| 在线阅读: | https://doi.org/10.1016/0304-3940(95)11902-9 |
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