Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms
The recent establishment of a robust hepatitis C virus (HCV) cell culture system permits analysis of virus-host interactions during HCV infection. Here, we report that HCV genotype 2a (JFH-1) infection fails to induce IFN-beta or IFN-stimulated gene expression in Huh-7 cells, and that it blocks IFN-...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | inglese |
| Pubblicazione: |
2006
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| Accesso online: | https://doi.org/10.1073/pnas.0602957103 |
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