Defective B cell responses in the absence of SH2D1A

More than half of patients with X-linked lympho-proliferative disease, which is caused by a defect in the intracellular adapter protein SH2D1A, suffer from an extreme susceptibility to Epstein-Barr virus. One-third of these patients, however, develop dysgammaglobulenemia without an episode of severe...

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Main Authors: Massimo Morra, Robert A. Barrington, Ana Clara Abadía‐Molina, Susumo Okamoto, Aimée Julien, Charles Gullo, Anuj Kalsy, Matthew Edwards, Gang Chen, Rosanne Spolski, Warren J. Leonard, Brigitte T. Huber, Persephone Borrow, Christine A. Biron, Abhay R. Satoskar, Michael C. Carroll, Cox Terhorst
格式: Artigo
语言:英语
出版: 2005
在线阅读:https://doi.org/10.1073/pnas.0408681102
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