Defective B cell responses in the absence of SH2D1A
More than half of patients with X-linked lympho-proliferative disease, which is caused by a defect in the intracellular adapter protein SH2D1A, suffer from an extreme susceptibility to Epstein-Barr virus. One-third of these patients, however, develop dysgammaglobulenemia without an episode of severe...
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Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Lenguaje: | inglés |
Publicado: |
2005
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Acceso en línea: | https://doi.org/10.1073/pnas.0408681102 |
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