Defective B cell responses in the absence of SH2D1A

More than half of patients with X-linked lympho-proliferative disease, which is caused by a defect in the intracellular adapter protein SH2D1A, suffer from an extreme susceptibility to Epstein-Barr virus. One-third of these patients, however, develop dysgammaglobulenemia without an episode of severe...

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Autores principales: Massimo Morra, Robert A. Barrington, Ana Clara Abadía‐Molina, Susumo Okamoto, Aimée Julien, Charles Gullo, Anuj Kalsy, Matthew Edwards, Gang Chen, Rosanne Spolski, Warren J. Leonard, Brigitte T. Huber, Persephone Borrow, Christine A. Biron, Abhay R. Satoskar, Michael C. Carroll, Cox Terhorst
Formato: Artigo
Lenguaje:inglés
Publicado: 2005
Acceso en línea:https://doi.org/10.1073/pnas.0408681102
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