Two Serine Residues Control Sequential Steps during Catalysis of the Yeast Copper ATPase through Different Mechanisms That Involve Kinase-mediated Phosphorylations
Ccc2, the yeast copper-transporting ATPase, pumps copper from the cytosol to the Golgi lumen. During its catalytic cycle, Ccc2 undergoes auto-phosphorylation on Asp(627) and uses the energy gained to transport copper across the cell membrane. We previously demonstrated that cAMP-dependent protein ki...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2010
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| Online Access: | https://doi.org/10.1074/jbc.m110.207704 http://www.jbc.org/article/S0021925820518814/pdf |
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