Identification of the Sites of Tau Hyperphosphorylation and Activation of Tau Kinases in Synucleinopathies and Alzheimer’s Diseases

ObjectiveMost neurodegenerative diseases contain hyperphosphorylated Tau [p-Tau]. We examined for the first time epitopes at which Tau is hyperphosphorylated in Parkinson’s disease, dementia with Lewy bodies and Alzheimer’s disease, and also select Tau kinases. MethodsPostmortem frontal cortex from...

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Main Authors: Valeriy Duka, Jae‐Hoon Lee, Joel J. Credle, Jonathan Wills, Adam W. Oaks, Ciaran Smolinsky, Ketul Shah, Deborah C. Mash, Eliezer Masliah, Anita Sidhu
Formato: Artigo
Idioma:inglés
Publicado: 2013
Acceso en liña:https://doi.org/10.1371/journal.pone.0075025
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0075025&type=printable
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