Principles of regulatory information conservation between mouse and human

Principles of regulatory information conservation between mouse and human

To broaden our understanding of the evolution of gene regulation mechanisms, we generated occupancy profiles for 34 orthologous transcription factors (TFs) in human–mouse erythroid progenitor, lymphoblast and embryonic stem-cell lines. By combining the genome-wide transcription factor occupancy repe...

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Main Authors: Yong Cheng, Zhihai Ma, Bong Hyun Kim, Wei-Sheng Wu, Philip Cayting, Alan P. Boyle, Vasavi Sundaram, Xiaoyun Xing, Nergiz Doğan, Jingjing Li, Ghia Euskirchen, Shin Lin, Yiing Lin, Axel Visel, Trupti Kawli, Xinqiong Yang, Dorrelyn Patacsil, Cheryl A. Keller, Belinda Giardine, Anshul Kundaje, Ting Wang, L Pennacchio, Zhiping Weng, Ross C. Hardison, M Snyder
Format: Artigo
Language:English
Published: 2014
Online Access:https://doi.org/10.1038/nature13985
https://www.nature.com/articles/nature13985.pdf
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https://doi.org/10.1038/nature13985
https://www.nature.com/articles/nature13985.pdf

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