Principles of regulatory information conservation between mouse and human

Principles of regulatory information conservation between mouse and human

To broaden our understanding of the evolution of gene regulation mechanisms, we generated occupancy profiles for 34 orthologous transcription factors (TFs) in human–mouse erythroid progenitor, lymphoblast and embryonic stem-cell lines. By combining the genome-wide transcription factor occupancy repe...

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Huvudupphovsmän: Yong Cheng, Zhihai Ma, Bong Hyun Kim, Wei-Sheng Wu, Philip Cayting, Alan P. Boyle, Vasavi Sundaram, Xiaoyun Xing, Nergiz Doğan, Jingjing Li, Ghia Euskirchen, Shin Lin, Yiing Lin, Axel Visel, Trupti Kawli, Xinqiong Yang, Dorrelyn Patacsil, Cheryl A. Keller, Belinda Giardine, Anshul Kundaje, Ting Wang, L Pennacchio, Zhiping Weng, Ross C. Hardison, M Snyder
Materialtyp: Artigo
Språk:engelska
Publicerad: 2014
Länkar:https://doi.org/10.1038/nature13985
https://www.nature.com/articles/nature13985.pdf
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