Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus

Norwalk virus (NV), the prototype human calicivirus, is the leading cause of nonbacterial acute gastroenteritis. The NV protease cleaves the polyprotein encoded by open reading frame 1 of the viral genome at five nonhomologous sites, releasing six nonstructural proteins that are essential for viral...

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Hlavní autoři: Zana Muhaxhiri, Lisheng Deng, Sreejesh Shanker, Banumathi Sankaran, Mary K. Estes, Timothy Palzkill, Yongcheng Song, B. V. Venkataram Prasad
Médium: Artigo
Jazyk:angličtina
Vydáno: 2013
On-line přístup:https://doi.org/10.1128/jvi.02869-12
https://jvi.asm.org/content/jvi/87/8/4281.full.pdf
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