A Mouse Model of Hemorrhagic Transformation by Delayed Tissue Plasminogen Activator Administration After In Situ Thromboembolic Stroke
thrombolytic treatment with tissue plasminogen activator (tPA) improves outcome of patients with stroke who can be treated within 3 hours of symptom onset. However, delayed treatment with tPA leads to increased risk of hemorrhagic transformation and can result in enhanced brain injury. The purpose o...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | anglès |
| Publicat: |
2010
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| Accés en línia: | https://doi.org/10.1161/strokeaha.110.600452 https://www.ahajournals.org/doi/pdf/10.1161/STROKEAHA.110.600452 |
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