Tetramethylpyrazine Produces Antidepressant-Like Effects in Mice Through Promotion of BDNF Signaling Pathway

Background:Current antidepressants are clinically effective only after several weeks of administration. Tetramethylpyrazine (TMP) is an identified component of Ligusticum wallichii with neuroprotective effects. Here, we investigated the antidepressant effects of TMP in mice models of depression.

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Autors principals: Bo Jiang, Chao Huang, Xiangfan Chen, Lijuan Tong, Wei Zhang
Format: Artigo
Idioma:anglès
Publicat: 2015
Accés en línia:https://doi.org/10.1093/ijnp/pyv010
https://academic.oup.com/ijnp/article-pdf/18/8/pyv010/14095148/pyv010.pdf
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