Loss of Methyl-CpG–Binding Domain Protein 2 Enhances Endothelial Angiogenesis and Protects Mice Against Hind-Limb Ischemic Injury
Background— Despite intensive investigation, how DNA methylation influences endothelial function remains poorly understood. We used methyl-CpG–binding domain protein 2 (MBD2), an interpreter for DNA methylome–encoded information, to dissect the impact of DNA methylation on endothelial function in bo...
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Main Authors: | , , , , , , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2011
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在线阅读: | https://doi.org/10.1161/circulationaha.110.966408 |
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