Bacterial topoisomerase I as a target for discovery of antibacterial compounds
Bacterial topoisomerase I is a potential target for discovery of new antibacterial compounds. Mutant topoisomerases identified by SOS induction screening demonstrated that accumulation of the DNA cleavage complex formed by type IA topoisomerases is bactericidal. Characterization of these mutants of...
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| Médium: | Revisão |
| Jazyk: | angličtina |
| Vydáno: |
2008
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| On-line přístup: | https://doi.org/10.1093/nar/gkn936 https://academic.oup.com/nar/article-pdf/37/3/731/7700029/gkn936.pdf |
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