Bacterial topoisomerase I as a target for discovery of antibacterial compounds
Bacterial topoisomerase I is a potential target for discovery of new antibacterial compounds. Mutant topoisomerases identified by SOS induction screening demonstrated that accumulation of the DNA cleavage complex formed by type IA topoisomerases is bactericidal. Characterization of these mutants of...
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| フォーマット: | Revisão |
| 言語: | 英語 |
| 出版事項: |
2008
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| オンライン･アクセス: | https://doi.org/10.1093/nar/gkn936 https://academic.oup.com/nar/article-pdf/37/3/731/7700029/gkn936.pdf |
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