Genetic variation in a haplotype block spanningIDE influences Alzheimer disease
Linkage studies have identified a large (>60-Mb) region on chromosome 10q that segregates with Alzheimer Disease (AD). Within the region, the gene for insulin degrading enzyme (IDE) represents a notable biological candidate given that it degrades amyloid β-protein (one of the major constituents o...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | inglés |
| Publicado: |
2003
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| Acceso en línea: | https://doi.org/10.1002/humu.10282 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/humu.10282 |
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