Decreased sickle red blood cell adhesion to laminin by hydroxyurea is associated with inhibition of Lu/BCAM protein phosphorylation

Geahča maid

• Aggregation of mononuclear and red blood cells through an α(4)β(1)-Lu/basal cell adhesion molecule interaction in sickle cell disease
  Dahkki: Chaar, Vicky, et al.
  Almmustuhtton: (2010)
• Hydroxycarbamide Decreases Sickle Reticulocyte Adhesion to Resting Endothelium by Inhibiting Endothelial Lutheran/Basal Cell Adhesion Molecule (Lu/BCAM) through Phosphodiesterase 4A Activation
  Dahkki: Chaar, Vicky, et al.
  Almmustuhtton: (2014)
• Increased adhesion to endothelial cells of erythrocytes from patients with polycythemia vera is mediated by laminin α5 chain and Lu/BCAM
  Dahkki: Marie‐Paule Wautier, et al.
  Almmustuhtton: (2007)
• Population pharmacokinetics and pharmacodynamics of hydroxyurea in sickle cell anemia patients, a basis for optimizing the dosing regimen
  Dahkki: Paule, Ines, et al.
  Almmustuhtton: (2011)
• Biological parameters predictive of percent dense red blood cell decrease under hydroxyurea
  Dahkki: Rakotoson, Marie Georgine, et al.
  Almmustuhtton: (2015)