Chemotaxis in a lymphocyte cell line transfected with C-C chemokine receptor 2B: Evidence that directed migration is mediated by βγ dimers released by activation of G<sub>αi</sub>-coupled receptors
Chemotaxis is mediated by activation of seven-transmembrane domain, G protein-coupled receptors, but the signal transduction pathways leading to chemotaxis are poorly understood. To identify G proteins that signal the directed migration of cells, we stably transfected a lymphocyte cell line (300-19)...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | inglés |
| Publicado: |
1997
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| Acceso en liña: | https://doi.org/10.1073/pnas.94.26.14495 |
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