Comparative Genomics Search for Losses of Long-Established Genes on the Human Lineage

Taking advantage of the complete genome sequences of several mammals, we developed a novel method to detect losses of well-established genes in the human genome through syntenic mapping of gene structures between the human, mouse, and dog genomes. Unlike most previous genomic methods for pseudogene...

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Autori principali: Jingchun Zhu, Zack Sanborn, Mark Diekhans, Craig B. Lowe, Tom H. Pringle, David Haussler
Natura: Artigo
Lingua:inglese
Pubblicazione: 2007
Accesso online:https://doi.org/10.1371/journal.pcbi.0030247
https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.0030247&type=printable
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