Attenuation of insulin secretion by insulin-like growth factor 1 is mediated through activation of phosphodiesterase 3B
Both insulin and insulin-like growth factor 1 (IGF-1) are known to reduce glucose-dependent insulin secretion from the β cells of pancreatic islets. In this paper we show that the mechanism by which IGF-1 mediates this effect is in large part through activation of a specific cyclic nucleotide phosph...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | angličtina |
| Vydáno: |
1997
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| On-line přístup: | https://doi.org/10.1073/pnas.94.7.3223 |
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