Attenuation of insulin secretion by insulin-like growth factor 1 is mediated through activation of phosphodiesterase 3B

Both insulin and insulin-like growth factor 1 (IGF-1) are known to reduce glucose-dependent insulin secretion from the β cells of pancreatic islets. In this paper we show that the mechanism by which IGF-1 mediates this effect is in large part through activation of a specific cyclic nucleotide phosph...

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Huvudupphovsmän: Allan Z. Zhao, Hong Zhao, Jeanette Teague, Wilfred Y. Fujimoto, Joseph A. Beavo
Materialtyp: Artigo
Språk:engelska
Publicerad: 1997
Länkar:https://doi.org/10.1073/pnas.94.7.3223
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