Correction of Defective Protein Kinesis of Human P-glycoprotein Mutants by Substrates and Modulators
There is growing evidence that abnormal protein folding or trafficking (protein kinesis) leads to diseases. We have used P-glycoprotein as a model protein to develop strategies to overcome defects in protein kinesis. Misprocessed mutants of the human P-glycoprotein are retained in the endoplasmic re...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | angličtina |
| Vydáno: |
1997
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| On-line přístup: | https://doi.org/10.1074/jbc.272.2.709 http://www.jbc.org/article/S0021925819775243/pdf |
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