Correction of Defective Protein Kinesis of Human P-glycoprotein Mutants by Substrates and Modulators

There is growing evidence that abnormal protein folding or trafficking (protein kinesis) leads to diseases. We have used P-glycoprotein as a model protein to develop strategies to overcome defects in protein kinesis. Misprocessed mutants of the human P-glycoprotein are retained in the endoplasmic re...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Tip W. Loo, David M. Clarke
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 1997
Rochtain ar líne:https://doi.org/10.1074/jbc.272.2.709
http://www.jbc.org/article/S0021925819775243/pdf
Clibeanna: Cuir clib leis
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!