Effect of MRE11 Loss on PARP-Inhibitor Sensitivity in Endometrial Cancer In Vitro
Aim of the study To evaluate the frequency of MRE11/RAD50/NBS1 (MRN)-complex loss of protein expression in endometrial cancers (EC) and to determine whether loss of MRE11 renders the cancer cells sensitive to Poly(ADP-ribose) polymerase (PARP)-inhibitory treatment. Methods MRN expression was examine...
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| Main Authors: | , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2014
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| 在線閱讀: | https://doi.org/10.1371/journal.pone.0100041 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0100041&type=printable |
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