KIM-1–mediated phagocytosis reduces acute injury to the kidney

Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. Here, we determined that early in the injury process, however, KIM-1 expression is antiinflammatory due to its mediation of phagocytic proc...

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Principais autores: Li Yang, Craig R. Brooks, Sheng Xiao, Venkata Sabbisetti, Melissa Y. Yeung, Li‐Li Hsiao, Takaharu Ichimura, Vijay K. Kuchroo, Joseph V. Bonventre
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Acesso em linha:https://doi.org/10.1172/jci75417
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