Mechanism of renal excretion of AM-715, a new quinolonecarboxylic acid derivative, in rabbits, dogs, and humans
The mechanisms of the renal excretion of AM-715, a synthetic antimicrobial agent, were studied in rabbits, dogs, and humans. In both rabbits and humans, AM-715 clearance was greater than creatinine clearance and was profoundly decreased by the administration of probenecid. Thus, in these subjects, A...
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| Auteurs principaux: | , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | anglais |
| Publié: |
1983
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| Accès en ligne: | https://doi.org/10.1128/aac.23.1.1 |
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