Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection

Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection

CD4+ T cell help is critical in maintaining antiviral immune responses and such help has been shown to be sustained in acute resolving hepatitis C. In contrast, in evolving chronic hepatitis C CD4+ T cell helper responses appear to be absent or short-lived, using functional assays.Here we used a nov...

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Main Authors: Michaela Lucas, Axel Ulsenheimer, Katja Pfafferot, Malte Heeg, Silvana Gaudieri, Norbert H. Grüner, Andri Rauch, J. Tilman Gerlach, Maria–Christina Jung, Roman Zachoval, Gerd R. Pape, Winfried Schraut, Teresa Santantonio, Hans Nitschko, Martin Obermeier, Rodney Phillips, Thomas J. Scriba, Nasser Semmo, Cheryl L. Day, Jonathan Weber, Sarah Fidler, Robert Thimme, Anita Haberstroh, Thomas F. Baumert, Paul Klenerman, Helmut M. Diepolder
Format: Artigo
Jezik:angleščina
Izdano: 2007
Online dostop:https://doi.org/10.1371/journal.pone.0000649
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000649&type=printable
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https://doi.org/10.1371/journal.pone.0000649
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000649&type=printable

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