Executioner caspase-3 and caspase-7 are functionally distinct proteases

Members of the caspase family of cysteine proteases play central roles in coordinating the stereotypical events that occur during apoptosis. Because the major executioner caspases, caspase-3 and caspase-7, exhibit almost indistinguishable activity toward certain synthetic peptide substrates, this ha...

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Autores principales: J. Walsh, Sean P. Cullen, Clare Sheridan, Alexander U. Lüthi, Christopher Gerner, Séamus J. Martin
Formato: Artigo
Lenguaje:inglés
Publicado: 2008
Acceso en línea:https://doi.org/10.1073/pnas.0707715105
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