Multi-Population Classical HLA Type Imputation

Statistical imputation of classical HLA alleles in case-control studies has become established as a valuable tool for identifying and fine-mapping signals of disease association in the MHC. Imputation into diverse populations has, however, remained challenging, mainly because of the additional haplo...

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Bibliographic Details
Main Authors: Alexander Dilthey, Stephen Leslie, Loukas Moutsianas, Judong Shen, Charles Cox, Matthew R. Nelson, Gil McVean
Format: Artigo
Language:English
Published: 2013
Online Access:https://doi.org/10.1371/journal.pcbi.1002877
https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002877&type=printable
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