Phosphatidylinositol phosphate 5-kinase Iβ recruits AP-2 to the plasma membrane and regulates rates of constitutive endocytosis
Overexpression of phosphatidylinositol phosphate 5-kinase (PIP5KI) isoforms α, β, or γ in CV-1 cells increased phosphatidylinositol 4,5-bisphosphate (PIP2) levels by 35, 180, and 0%, respectively. Endocytosis of transferrin receptors, association of AP-2 proteins with membranes, and the number of cl...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2003
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| Online Access: | https://doi.org/10.1083/jcb.200302051 https://rupress.org/jcb/article-pdf/162/4/693/1310740/jcb1624693.pdf |
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