Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease
Dopaminergic cell death in the substantia nigra (SN) is central to Parkinson's disease (PD), but the neurodegenerative mechanisms have not been completely elucidated. Iron accumulation in dopaminergic and glial cells in the SN of PD patients may contribute to the generation of oxidative stress,...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Acesso em linha: | https://doi.org/10.1073/pnas.0804373105 |
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